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ASH Image Bank (2002); doi:10.1182/ashimagebank-2002-100503
Copyright © 2002 by the American Society of Hematology.
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Atlas Image Set
Gaucher's Disease
John Lazarchick, MD
Medical University of South Carolina
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Figure 1.
The bone marrow aspirate illustrates the characteristic feature of Gaucher cells (arrows) with "wrinkled paper" cytoplasm.
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Figure 2.
The distinct cytoplasmic features are more evident on this higher powered view of the same cells as in Figure 1.
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Figure 3.
Periodic Acid-Schiff (PAS) stain of the Gaucher cells (arrows).
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Figure 4.
The Gaucher cells are also positive with acid phosphatase histochemical stain.
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Figure 5.
Bone marrow biopsy illustrates a diffuse infiltrate of large, pale-appearing cells (arrows) with normal hematopoietic elements in the background.
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Figure 6.
A higher power view of the cells shown in Figure 5 is shown here.
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Related ASH-SAP Chapter:
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This Article
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Articles by Lazarchick, J.
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Articles by Lazarchick, J.
Related Collections
Lipid Storage Disorders: Gaucher's disease, Nieman Pick
Related ASH-SAP Chapter
Related Image Bank Image Sets
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Copyright © 2002 by the American Society of Hematology.