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ASH Image Bank (2002); doi:10.1182/ashimagebank-2002-100503
Copyright © 2002 by the American Society of Hematology.
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Atlas Image Set

Gaucher's Disease

John Lazarchick, MD

Medical University of South Carolina



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Figure 1. The bone marrow aspirate illustrates the characteristic feature of Gaucher cells (arrows) with "wrinkled paper" cytoplasm.

 


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Figure 2. The distinct cytoplasmic features are more evident on this higher powered view of the same cells as in Figure 1.

 


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Figure 3. Periodic Acid-Schiff (PAS) stain of the Gaucher cells (arrows).

 


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Figure 4. The Gaucher cells are also positive with acid phosphatase histochemical stain.

 


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Figure 5. Bone marrow biopsy illustrates a diffuse infiltrate of large, pale-appearing cells (arrows) with normal hematopoietic elements in the background.

 


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Figure 6. A higher power view of the cells shown in Figure 5 is shown here.

 

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Related ASH-SAP Chapter:space logo
Chapter 7: Myeloid disorders

This Article
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Citing Articles
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Right arrow Articles by Lazarchick, J.
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PubMed
Right arrow Articles by Lazarchick, J.
Related Collections
Right arrow Lipid Storage Disorders: Gaucher's disease, Nieman Pick
Right arrow Related ASH-SAP Chapter
Right arrowRelated Image Bank Image Sets
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Copyright © 2002 by the American Society of Hematology.