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ASH Image Bank (2003); doi:10.1182/ashimagebank-2003-100948
Copyright © 2003 by the American Society of Hematology.
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Atlas Image Set
Acute Monoblastic Leukemia
Peter Maslak
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Figure 1.
Blasts circulating in the peripheral blood.
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Figure 2.
In the peripheral blood, blasts appear much larger than red cells. Even at this low power, vacuoles are noted.
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Figure 3.
Blasts appear to have ample cytoplasm and a smooth chromatin pattern.
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Figure 4.
Blasts are the predominant population in the bone marrow.
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Figure 5.
Leukemic monoblasts display abundant cytoplasm, fine granulation and vacuoles.
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Figure 6.
Abnormal monocytic elements may have a delicate chromatin pattern.
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Figure 7.
Leukemic monoblasts with increased azurophilic granules. One of these (arrow) appears to have a cytoplasmic "tail".
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Figure 8.
In the acute monocytic leukemias, 80% or more of the nonerythroid cells are of monocytic lineage.
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Figure 9.
Cells with fine granulation and vacuoles.
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Figure 10.
Nonspecific esterase positivity defines monocytic lineage. The deeply staining cells are considered positive.
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Related ASH-SAP Chapter:
Chapter 10: Acute myeloid leukemia
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Copyright © 2003 by the American Society of Hematology.