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Anorexia Nervosa - Arrow Morphology

View larger version (169K): [in this window] [in a new window]   Figure 1. 25 year old white female with a history of an eating disorder presented with pancytopenia. A low-power view of her marrow aspirate shows scattered hematopoietic cells in a background of a pink amorphous infiltrate. (Wright-Giemsa 4x)

View larger version (155K): [in this window] [in a new window]   Figure 2. Hematopoietc elements icluding erythroid precursors and megakaryocytes can be recognized in addition to a few fat cells. The amorphous material represents depositionof hyaluronic acid with gelatinous transformation of the marrow. (W-G 10x)

View larger version (159K): [in this window] [in a new window]   Figure 3. At a higher magnification the extracellular matrix deposition has a fibrillar appearance. (W-G 40x)

View larger version (158K): [in this window] [in a new window]   Figure 4. A marrow biopsy is shown illustrating almost complete replacement of the marrow by the hyaluronic acid extracellular matrix material. Hematopoietic elements and fat cells are markedly decreased. (H&E 4x)

View larger version (164K): [in this window] [in a new window]   Figure 5. A higher magnification shows the presence of isolated erythroid islands in addition to occasional myeloid and megakaryocytic elements. The mucopolysaccharide deposition appears pink on H&E staining. (H&E 10x)

View larger version (160K): [in this window] [in a new window]   Figure 6. A higher magnification of the previous image is shown. Note the granular appearance of the background extracellular matrix material. (H&E 40x)

View larger version (144K): [in this window] [in a new window]   Figure 7. Terminally differentiated erythroid and myeloid cells are prominent in this view. Early precursor cells of both of these cell lines are rare. (H&E 40x)

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This Article Figures Only Services Similar articles in this journal Alert me to new content in the Image Bank Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Lazarchick, J. Articles by Stevenson, M. Search for Related Content PubMed Articles by Lazarchick, J. Articles by Stevenson, M. Related Collections Anorexia nervosa, starvation Related ASH-SAP Chapter Related Image Bank Image Sets Social Bookmarking                   What's this?