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ASH Image Bank (2004); doi:10.1182/ashimagebank-2004-101038
Copyright © 2004 by the American Society of Hematology.
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Atlas Image Set

Juvenile Myelomonocytic Leukemia

Peter Maslak



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Figure 1. Peripheral blood shows a leukocytosis consisting of dysplastic granulocytes, monocytes and eosinophils.

 


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Figure 2. Dysplastic granulocytes are noted along with an eosinophil.

 


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Figure 3. Peripheral blood with dysplastic granulocytes and monocyte.

 


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Figure 4. Blasts can be found in the peripheral blood but generally account for less than 5% of the white cells.

 


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Figure 5. A variety of red cell changes may be present.

 


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Figure 6. Nucleated RBCs are often seen in the peripheral blood.

 


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Figure 7. Eosinophils may be seen in the peripheral blood but are found in a minority of patients.

 


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Figure 8. The bone marrow aspirate is hypercellular with granulocytic hyperplasia.

 


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Figure 9. Spectrum of myeloid maturation with a left shift is noted.

 


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Figure 10. Cells lack the Ph chromosome or the BCR-ABL fusion gene.

 


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Figure 11. Myeloid elements are increased and differentiation is left shifted.

 

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Related ASH-SAP Chapter:space logo
Chapter 9: Myelodysplastic syndrome and overlap syndromes

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Copyright © 2004 by the American Society of Hematology.