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ASH Image Bank (2004); doi:10.1182/ashimagebank-2004-101081
Copyright © 2004 by the American Society of Hematology.
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Atlas Image Set

Sézary Cells

John Lazarchick



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  		Figure 1. A buffy coat preparation on the peripheral blood from a patient with confirmed mycosis fungoides is shown. A prolymphocytes is noted centrally but the majority of cells present are small lymphocytes with minimal cytoplasm. Nuclear detail can not be appreciated at this magnification. (Wright-Giemsa 40x)

 


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  		Figure 2. At a higher magnification the irregularity of the nuclear borders of the cells are now readily seen. In addition, several of the cells show nuclear cleaving and the nuclei have a cerebriform appearance. The cells have a minimal amount of agranular basophilic cytoplasm. (Wright-Giemsa 100x)

 


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  		Figure 3. The nuclear convolutions are most apparent in the cell in the center in this view. The cell to the left shows nuclear grooving with overlapping nuclear lobes.

 

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Related ASH-SAP Chapter:space logo
Chapter 12: Lymphoproliferative disorders

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Right arrow T-Cell and NK-Cell Neoplasms
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Copyright © 2004 by the American Society of Hematology.