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Acute Leukemia of Ambiguous Lineage

View larger version (130K): [in this window] [in a new window]   Figure 1. Blast in the peripheral blood. This cell lacks granules or Auer rods, features which are associated with myeloid lineage.

View larger version (132K): [in this window] [in a new window]   Figure 2. Few granules can be seen in this blast. The nucleus is irregular. Cell surface markers are of both myeloid and lymphoid lineage.

View larger version (134K): [in this window] [in a new window]   Figure 3. Elongated blast with few granules in the cytoplasm. A prominent nucleolus is noted.

View larger version (143K): [in this window] [in a new window]   Figure 4. Blasts are markedly increased. Few normal elements are noted.

View larger version (139K): [in this window] [in a new window]   Figure 5. Abnormal folding of the nucleus is seen in some of the cells. In addition, some of the blasts have an irregular nuclear contour.

View larger version (149K): [in this window] [in a new window]   Figure 6. A coarse chromatin pattern is noted in some of the blasts.

View larger version (128K): [in this window] [in a new window]   Figure 7. Blasts vary in the amount of cytoplasm.

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