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ASH Image Bank (2004); doi:10.1182/ashimagebank-2004-101133
Copyright © 2004 by the American Society of Hematology.
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Atlas Image Set

Sarcoidosis

John Lazarchick



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  		Figure 1. Bone marrow biopsy reveals a hyper-cellular marrow with multiple non-caseating granulomas(arrows). Normal hematopoietic elements are evident in the remainder of the marrow. (H&E 10x)

 


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  		Figure 2. Two large granulomatous lesions are present. The upper lesion is surrounded by a lymphoid aggregate as part of the granulomatous inflammatory reaction.

 


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  		Figure 3. Benign-appearing macrophages comprising the lesions are show. Lymphocytes and eosinphils are noted in the background.

 


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  		Figure 4. Loose aggregate of macrophages and scattered lymphocytes comprise the granuloma. Caseous necrosis is absent.

 


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  		Figure 5. The lesions were negative for acid-fast bacilli on histochemical staining (Z-N 40x). Similarly, a histochemical stain for fungus was also negative (not shown).

 

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Related ASH-SAP Chapter:space logo
Chapter 18: Consultative hematology

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Right arrow Figures Only
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Right arrow Sarcoidosis
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Copyright © 2004 by the American Society of Hematology.