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Refractory Anemia with Ring Sideroblasts

View larger version (136K): [in this window] [in a new window]   Figure 1. Bone marrow aspirate is hypercellular with erythroid hyperplasia and prominent dyserythropoiesis.

View larger version (128K): [in this window] [in a new window]   Figure 2. Nuclear-cytoplasmic asynchrony is characteristic of dysplastic erythroid elements.

View larger version (126K): [in this window] [in a new window]   Figure 3. Prussian blue stain is used to identify ring sideroblasts.

View larger version (139K): [in this window] [in a new window]   Figure 4. Iron may be distributed in the mitochondria in a typical "necklace" pattern around the nucleus or as large clusters within the cytoplasm.

View larger version (113K): [in this window] [in a new window]   Figure 5. Ring sideroblasts are formed by abnormal deposition of iron in the mitochondria surrounding the nucleus of red cell precursors.

View larger version (165K): [in this window] [in a new window]   Figure 6. Sideroblasts constitute greater than 15% of the erythroblasts.

View larger version (174K): [in this window] [in a new window]   Figure 7. RARS accounts for approximately 15%-20% of the myelodysplastic syndromes.

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This Article Figures Only Services Similar articles in this journal Alert me to new content in the Image Bank Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Maslak, P. Search for Related Content PubMed Articles by Maslak, P. Related Collections Myelodysplastic Syndromes Related ASH-SAP Chapter Related Image Bank Image Sets Related ASH Education Book Articles Social Bookmarking                   What's this?