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ASH Image Bank (2004); doi:10.1182/ashimagebank-2004-101136
Copyright © 2004 by the American Society of Hematology.
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Atlas Image Set

Basophilic Stippling - Lead Poisoning

John Lazarchick



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Figure 1. Peripheral smear from a 3-year-old with history of pica who had a hemoglobin of 9.5 g/dL. RBCs are normochromic/normocytic but polychromatophilic cells are markedly hypochromic and contain multiple coarse basophilic granules. (W-G 50x)

 


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Figure 2. The coarse basophilic stippling is most prominent in the younger (poly-chromatophilic)RBCs, a typical finding in lead intoxication.

 


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Figure 3. Although the coarse stippling is most prominent in the polychromatophilic cells, the mature RBCs noted in the center of the slide also have similar single inclusions.

 


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Figure 4. Another example of the coarse basophilic inclusions, primarily limited to the younger polychromatophilic cells.

 

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Related ASH-SAP Chapter:space logo
Chapter 6: Hemolytic anemias

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Copyright © 2004 by the American Society of Hematology.