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ASH Image Bank (2004); doi:10.1182/ashimagebank-2004-101198
Copyright © 2004 by the American Society of Hematology.
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Atlas Image Set

Chronic Myelomonocytic Leukemia

Peter Maslak



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Figure 1. Peripheral blood smear reveals a monocytosis with dysplastic granulocytes.

 


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Figure 2. High power view of a monocyte circulating in the peripheral blood of a patient with CMMoL.

 


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Figure 3. In this disorder, granulocytes may have dysplastic features. This neutrophil exhibits hyperlobulation of the nucleus reminiscent of myeloid cells found in megaloblastic anemia.

 


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Figure 4. The bone marrow has increased mononuclear forms. Blasts constitute less than 20% of the nucleated cells.

 


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Figure 5. Monocytes and promonocytes may be the predominent population in the bone marrow.

 


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Figure 6. Some of the monocytes may appear abnormal with unusual features such as accentuated folding of the nucleus.

 

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Related ASH-SAP Chapter:space logo
Chapter 9: Myelodysplastic syndrome and overlap syndromes

This Article
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Copyright © 2004 by the American Society of Hematology.