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Hereditary Elliptocytosis

View larger version (124K): [in this window] [in a new window]   Figure 1. An 8 year old male who was being evaluated for an upper respiratory infection was noted to be mildly anemic on his CBC. A peripheral blood smear at low magnification shows that the vast majority of the RBCs to have an elliptical shape. A minor population of normal shaped RBCs can be seen scattered throughout the smear.

View larger version (121K): [in this window] [in a new window]   Figure 2. At a higher magnification, the predominance of the elliptical shaped RBCs is even more apparent. In addition a few RBCs with irregularities of their cytoplasmic borders or with cytoplasmic protrustions can be seem.

View larger version (119K): [in this window] [in a new window]   Figure 3. The typical morphology of RBCs seen in hereditary elliptocytosis are shown in this view. Some of these cells exhibit a classical elongated cigar shape.

View larger version (88K): [in this window] [in a new window]   Figure 4. Helmet-like cells and other RBCs with cytoplasmic projections are noted in this view. An RBC with basophilic stippling is also illustrated (arrow).

View larger version (73K): [in this window] [in a new window]   Figure 5. In this view acanthocytes are also present (RBCs with multiple cytoplasmic projections of variable length and thickness).

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This Article Figures Only Services Similar articles in this journal Alert me to new content in the Image Bank Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Lazarchick, J. Search for Related Content PubMed Articles by Lazarchick, J. Related Collections Hemolytic Disorders Related ASH-SAP Chapter Related Image Bank Image Sets Related ASH Education Book Article Social Bookmarking                   What's this?