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Dysplastic Red Cell Changes (Bone Marrow Aspirate) I

View larger version (117K): [in this window] [in a new window]   Figure 1. Aberrant mitosis: Arrows mark cells with fragments of disassociated chromatin.

View larger version (121K): [in this window] [in a new window]   Figure 2. Nuclear blebs: Black arrows mark a cell with a nuclear bud or bleb. Red arrows highlight anomalous mitotic figures.

View larger version (132K): [in this window] [in a new window]   Figure 3. Multinuclearity: Arrow marks a large multinucleated proerythroblast.

View larger version (130K): [in this window] [in a new window]   Figure 4. Megablastoid maturation: The giant cell in the center shows megablastoid changes -- large blocks of aggregated chromatin separated by lighter areas (parachromatin). Such a pattern imparts an "open" appearance to the nuclei.

View larger version (93K): [in this window] [in a new window]   Figure 5. Megaloblastic maturation: These cells (arrow) have chromatin with a fine, delicate appearance.

View larger version (140K): [in this window] [in a new window]   Figure 6. Asynchronous maturation (arrows). The chromatin pattern of these cells is fine, suggesting relative immaturity, while the lightening of the cytoplasm indicative of hemoglobinization is an event associated with maturation.

View larger version (77K): [in this window] [in a new window]   Figure 7. Gigantism: The large size of this basophilic cell with fine chromatin can be appreciated when contrasted with the surrounding red cells.

View larger version (44K): [in this window] [in a new window]   Figure 8. Gigantism: The red cell precursor is larger than its normal counterpart. This can be appreciated when comparing the size to other cells in the field.

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This Article Figures Only Services Similar articles in this journal Alert me to new content in the Image Bank Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Maslak, P. Search for Related Content PubMed Articles by Maslak, P. Related Collections Myelodysplastic Syndromes Related ASH-SAP Chapter Related Image Bank Image Sets Related ASH Education Book Articles Social Bookmarking                   What's this?