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ASH Image Bank (2008); doi:10.1182/ashimagebank-2008-8-00025
Copyright © 2008 by the American Society of Hematology.
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Atlas Image Set

Dysgranulopoiesis

Peter Maslak, M.D.


Figure 1
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Figure 1. Hypersegmented nuclei have more than the 3–5 lobes found in a typical granulocyte.

 

Figure 2
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Figure 2. Hypolobulation of the nucleus: multiple myeloid forms with varying degrees of hypolobulation.

 

Figure 3
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Figure 3. Pseudo-Pelger Huet cell with characteristic bisegmented nucleus.

 

Figure 4
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Figure 4. Arrow points to a "rodent" cell with a characteristic ringed or doughnut shaped nucleus. The cytoplasm contains multiple Döhle bodies.

 

Figure 5
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Figure 5. Aberrant mitotic figure with a relatively mature appearing cytoplasm.

 

Figure 6
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Figure 6. Hypergranulation: abundant granules similar to the appearance seen in toxic granulation.

 

Figure 7
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Figure 7. Hypogranulation: arrow points to a myeloid precursor with relative absence of secondary granules. The cytoplasm takes on a bluish-gray hue.

 

Figure 8
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Figure 8. Apoptotic form with degraded nuclear fragments.

 

Figure 9
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Figure 9. Myeloid arrest: relatively homogenous population of immature myeloid precursors without evidence of more mature forms.

 

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Hematopathological Concepts and Controversies in the Diagnosis and Classification of Myelodysplastic Syndromes
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Hematology 2008 2008: 52-59. [Abstract] [Full Text]



Related ASH-SAP Chapter:space logo
Chapter 9: Myelodysplastic syndrome and overlap syndromes

This Article
Right arrow Figures Only
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new content in the Image Bank
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Maslak, P.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Maslak, P.
Related Collections
Right arrow Myelodysplastic/myeloproliferative Disease
Right arrow Related ASH-SAP Chapter
Right arrowRelated Image Bank Image Sets
Right arrowRelated ASH Education Book Articles
Social Bookmarking
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Copyright © 2008 by the American Society of Hematology.