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Indolent systemic mastocytosis

View larger version (131K): [in this window] [in a new window]   Figure 1. This bone marrow core biopsy from a 57-year-old Caucasian man with a 15-year history of flushing and syncopal episodes due to indolent systemic mastocytosis shows sheets of mast cells (spindle shaped nuclei and abundant pink cytoplasm). Blood counts and skin were normal. (H&E 200x)

View larger version (92K): [in this window] [in a new window]   Figure 2. Mast cells stain positive (brown) for CD117 (c-kit). C-kit D816V mutation was detected in the bone marrow. (400x)

View larger version (127K): [in this window] [in a new window]   Figure 3. Mast cells stain positive (brown) for tryptase. Serum tryptase level was elevated at 45.9 ng/ml (normal 2–10). (200x)

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This Article Figures Only Services Similar articles in this journal Alert me to new content in the Image Bank Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Kudva, G. C. Articles by Grosso, L. E Search for Related Content PubMed Articles by Kudva, G. C. Articles by Grosso, L. E Related Collections Mast Cell Disease Related ASH-SAP Chapter Related Image Bank Image Sets Related ASH Education Book Article Social Bookmarking                   What's this?