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Kikuchi's lymphadenitis

View larger version (183K): [in this window] [in a new window]   Figure 1. Kikuchi’s lymphadenopathy is a necrotizing adenopathy of uncertain etiology. It is seen most commonly in Asiatic population and predominantly in young women. Usually the cervical nodes are involved; however, any nodal area may be involved, and systemic symptoms may be part of the presentation. The course is benign with spontaneous resolution occurring over weeks to months. Although the nodal architecture may be partially intact, the prominent feature of the disorder is patchy areas of necrosis randomly distributed throughout the node with histiocytic proliferation. An area of necrosis is shown on the image. In addition, there are areas of amorphous fibrinoid deposition present.

View larger version (182K): [in this window] [in a new window]   Figure 2. The heterogeneity of the inflammatory lesion can be seen in this view. Histiocytes, plasma cells and lymphocytes are prominent. Of note, there is an absence of neutrophils and eosinophils.

View larger version (172K): [in this window] [in a new window]   Figure 3. The characteristic lesion is shown at higher magnification in this view. Note the extensive pyknosis and karryorhexis. Nuclear fragments and histiocytic proliferation are prominent. As previously noted, plasma cells and lymphocytes are readily identified, but neutrophils are not seen in the necrotizing lesions.

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This Article Figures Only Services Similar articles in this journal Alert me to new content in the Image Bank Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Lazarchick, J. Search for Related Content PubMed Articles by Lazarchick, J. Related Collections Reactive Conditions of Lymph Nodes and Spleen Related Image Bank Image Sets Social Bookmarking                   What's this?