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ASH Image Bank (2008); doi:10.1182/ashimagebank-2008-8-00111
Copyright © 2008 by the American Society of Hematology.
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Atlas Image Set

Lymphomatous peritoneal effusion

John Lazarchick, M.D.


Figure 1
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Figure 1. A Wright stained smear of ascitic fluid obtained from a patient who presented with signs and symptoms of peritonitis is shown. There is a marked leukocytosis consisting primarily of neutrophils. In addition large cells with basophilic cytoplasm, round to irregular nuclei and prominent nucleoli are also present (arrow).

 

Figure 2
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Figure 2. A higher magnification of the previous image is shown. The heterogeneity in size and nuclear contour of the atypical cellular infiltrate is more evident. On flow cytometric analysis these cells marked as CD19, CD20 positive with kappa light chain restriction consistent with lymphomatous involvement of the peritoneum.

 

Figure 3
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Figure 3. The neoplastic features of these cells are most evident in this image. The cells have extensive agranular basophilic cytoplasm, variability in nuclear contours and one or more prominent nucleoli. A mitotic figure is also noted. A subsequent gastric biopsy confirmed the diagnosis of diffuse large B-cell lymphoma (DLBCL) in this patient.

 

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Related ASH-SAP Chapter:space logo
Chapter 12: Lymphoproliferative disorders

This Article
Right arrow Figures Only
Services
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Right arrow Alert me to new content in the Image Bank
Right arrow Download to citation manager
Citing Articles
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Google Scholar
Right arrow Articles by Lazarchick, J.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Lazarchick, J.
Related Collections
Right arrow B-Cell Neoplasms
Right arrow Related ASH-SAP Chapter
Right arrowRelated Image Bank Image Sets
Right arrowRelated ASH Education Book Articles
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Copyright © 2008 by the American Society of Hematology.