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Dermatopathic lymphadenopathy

View larger version (165K): [in this window] [in a new window]   Figure 1. An axillary lymph node from a patient with psoriasis is shown. The architectural structure of the node is intact. Irregularly shaped pale staining areas extending from the capsule into deeper areas of the node are typical of dermatopathic lymphadenopathy. The pallor is due to histiocyte proliferation in the paracortical regions of the node. These histiocytes may contain melanin pigment, lipid or hemosiderin.

View larger version (170K): [in this window] [in a new window]   Figure 2. More extensive histiocytic proliferation is shown in this view. Note there is capsular thickening suggesting a chronic process.

View larger version (175K): [in this window] [in a new window]   Figure 3. At higher magnification intermingled among the expanded histiocytic proliferative process are plasma cells, lymphocytes, and eosinophils.

View larger version (177K): [in this window] [in a new window]   Figure 4. The pale staining histiocytes are most evident in this view. The cells show abundant pink staining cytoplasm and have irregularly shaped nuclei without nucleoli. Intermingled esosinophils can also be seen.

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Related Image Bank Image Set

Kikuchi's lymphadenitis

John Lazarchick
ASH Image Bank 2008 2008: 800093. [Full Text]

Related ASH-SAP Chapter:

This Article Figures Only Services Similar articles in this journal Alert me to new content in the Image Bank Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Lazarchick, J. Search for Related Content PubMed Articles by Lazarchick, J. Related Collections Reactive Conditions of Lymph Nodes and Spleen Related ASH-SAP Chapter Related Image Bank Image Set Social Bookmarking                   What's this?