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Systemic mastocytosis involving lymph nodes

View larger version (183K): [in this window] [in a new window]   Figure 1. A low-power view of a lymph node from a patient with systemic mastocytosis is shown. Residual follicular structures can be identifies. The interfollicular space has multiple pale appearing areas composed of intermediate sized cells with abundant cytoplasm. Vascular structures are prominent in these regions. No definitive areas of fibrosis are evident.

View larger version (176K): [in this window] [in a new window]   Figure 2. In this image, the border of the pale staining mast cell infiltration is surrounded by eosinophils and lymphocytes. Vascular elements are present within the infiltrate.

View larger version (172K): [in this window] [in a new window]   Figure 3. The mast cell infiltrate can be seen to be perivascular in this view.

View larger version (169K): [in this window] [in a new window]   Figure 4. The same image at higher magnification is shown. Note the mast cells appear bland with abundant cytoplasm and have round to irregular nuclear borders. Eosinophils and lymphocytes can also be seen at the border of the infiltrate.

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This Article Figures Only Services Similar articles in this journal Alert me to new content in the Image Bank Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Lazarchick, J. Search for Related Content PubMed Articles by Lazarchick, J. Related Collections Mast Cell Disease Related ASH-SAP Chapter Related Image Bank Image Sets Related ASH Education Book Article Social Bookmarking                   What's this?