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"Mummified" megakaryocytes

View larger version (141K): [in this window] [in a new window]   Figure 1. The patient is a 22-year-old Hispanic male with HIV/AIDS who presented with fever and decreasing platelet count. A bone marrow biopsy showed a large number of atypical megakaryocytes (see arrows) with condensed nuclear lobation ("mummified" megakaryocytes). Normal appearing megakaryocytes are also noted. There were no dysplastic features to the erythroid or myeloid elements. Cytogenetics showed normal male karyotype.

View larger version (129K): [in this window] [in a new window]   Figure 2. The megakaryocyte atypia is more evident at this magnification with condensed nuclear lobes noted in these cells in comparison to the normal multilobated forms also present.

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This Article Figures Only Services Similar articles in this journal Alert me to new content in the Image Bank Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Lazarchick, J. Search for Related Content PubMed Articles by Lazarchick, J. Related Collections HIV/AIDS - lymphopenia Related ASH-SAP Chapter Related Image Bank Image Sets Related ASH Education Book Article Social Bookmarking                   What's this?