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ASH Image Bank (2009); doi:10.1182/ashimagebank-2009-8-00165
Copyright © 2009 by the American Society of Hematology.
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Atlas Image Set

Paroxysmal nocturnal hemoglobinuria

Peter Maslak, M.D.


Figure 1
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Figure 1. Flow cytometric demonstration of the absence of CD59 on erythroid cells has become the standard by which PNH is diagnosed. This is a single parameter histogram which demonstrates 3 populations of erythrocytes in a patient with PNH. Type I cells are normal residual erythroyctes. Type III cells are PNH cells with complete deficiency of CD59 while Type II cells are PNH cells with partial deficiency.

 

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Figure 2. The appearance of the marrow in PNH can be variable. In this patient with significant hemolysis, the marrow is hypercellular with erythroid hyperplasia.

 

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This Article
Right arrow Figures Only
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Right arrow Similar articles in this journal
Right arrow Alert me to new content in the Image Bank
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Maslak, P.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Maslak, P.
Related Collections
Right arrow Hemolytic Disorders
Right arrowRelated Image Bank Image Sets
Right arrowRelated ASH Education Book Articles
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Copyright © 2009 by the American Society of Hematology.