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Bone marrow granuloma

View larger version (144K): [in this window] [in a new window]   Figure 1. Non-caseating granulomatous lesion noted on bone marrow biopsy (arrows). The collection of benign appearing macrophages is interspersed with small lymphocyte and rare plasma cells.

View larger version (138K): [in this window] [in a new window]   Figure 2. The granulomatous lesion is shown at higher magnification to illustrate the cellular composition of macrophages with eosinophilic cytoplasm and scattered lymphocytes and plasma cells.

View larger version (151K): [in this window] [in a new window]   Figure 3. The lesion is circumscribed by a cuff of eosinophils (arrows).

View larger version (162K): [in this window] [in a new window]   Figure 4. A single multinucleated giant cells is shown (arrow).

View larger version (155K): [in this window] [in a new window]   Figure 5. A CD68 immunohistochemical is shown and illustrates the macrophage composition of the granuloma. The ACE level in this patient was elevated consistent with a clinical diagnosis of sarcoidosis.

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This Article Figures Only Services Similar articles in this journal Alert me to new content in the Image Bank Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Lazarchick, J. Search for Related Content PubMed Articles by Lazarchick, J. Related Collections Bone marrow manifestations of inflammatory or other systemic (non-infectious disease) Related ASH-SAP Chapter Related Image Bank Image Sets Related ASH Education Book Articles Social Bookmarking                   What's this?