HOME HELP FEEDBACK SEARCH		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Services Similar articles in this journal Alert me to new content in the Image Bank Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Lazarchick, J. Search for Related Content PubMed Articles by Lazarchick, J. Related Collections Acute Myeloid Leukemia Related ASH-SAP Chapter Related Image Bank Image Sets Related ASH Education Book Articles Social Bookmarking                   What's this?

AML with t(15;17)(q22;q21), microgranular variant

View larger version (70K): [in this window] [in a new window]   Figure 1. Peripheral smear from a patient with microgranular variant of AML-M3 (WHO AML with t('15;17)(q22;q12). The microgranular promyelocyte on the left has the classical bilobed nuclear shape with scant azurophilic granules in the cytoplasm. A faggot cell is shown in the middle with bundles of Auer rods. The promyelocyte on the right has a loculated, cerebriform-like nucleus and a few azurophilic granules.

View larger version (67K): [in this window] [in a new window]   Figure 2. The faggot cell is shown at higher magnification better illustrating the bundles of Auer rods.

View larger version (80K): [in this window] [in a new window]   Figure 3. Bone marrow aspirate from this case shows the spectrum of nuclear shapes characteristic of microgranular AML-M3. Blast cells with high nuclear/cytoplasmic ratios can be seen in the center of the image. Bilobed promyelocytes are scattered throughout thesmear showing variable cytoplasmic granularity. A few promyelocytes have a irregular cerebriform nuclear shape. One of the abnormal promyelcytes shows cytoplasmic vacuolization.

CiteULike

Connotea

Del.icio.us

Digg

Reddit

Technorati

Related Image Bank Image Sets

Acute Promyelocytic Leukemia

Peter Maslak
ASH Image Bank 2002 2002: 100364. [Full Text]

Hyperbasophilic Variant of Acute Promyelocytic Leukemia

Peter Maslak and Susan McKenzie
ASH Image Bank 2002 2002: 100585. [Full Text]

Microgranular Variant of Acute Promyelocytic Leukemia

Peter Maslak and Susan McKenzie
ASH Image Bank 2002 2002: 100598. [Full Text]

Hypergranulated Acute Promyelocytic Leukemia

Peter Maslak
ASH Image Bank 2003 2003: 100688. [Full Text]

Faggot cell

Peter Maslak
ASH Image Bank 2008 2008: 700039. [Full Text]

Related ASH Education Book Articles

Treatment of Acute Promyelocytic Leukemia

Miguel A. Sanz
Hematology 2006 2006: 147-155. [Abstract] [Full Text]

The Biology of Acute Promyelocytic Leukemia and Its Impact on Diagnosis and Treatment

Francesco Lo-Coco and Emanuele Ammatuna
Hematology 2006 2006: 156-161. [Abstract] [Full Text]

Curative Strategies in Acute Promyelocytic Leukemia

Martin S. Tallman and Jessica K. Altman
Hematology 2008 2008: 391-399. [Abstract] [Full Text]

Related ASH-SAP Chapter:

This Article Figures Only Services Similar articles in this journal Alert me to new content in the Image Bank Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Lazarchick, J. Search for Related Content PubMed Articles by Lazarchick, J. Related Collections Acute Myeloid Leukemia Related ASH-SAP Chapter Related Image Bank Image Sets Related ASH Education Book Articles Social Bookmarking                   What's this?