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ASH Image Bank (2009); doi:10.1182/ashimagebank-2009-9-00040
Copyright © 2009 by the American Society of Hematology.
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Atlas Image Set

Neonatal alloimmune hemolytic anemia due to ABO incompatibility

John Lazarchick, M.D.


Figure 1
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Figure 1. Peripheral smear from a newborn with neonatal alloimmune hemolytic anemia due to ABO incompatibility is illustrated. Mother was type O/Rh+, and newborn was type B/Rh+. The spectrum of RBC abnormalities in this disorder is shown including numerous nucleated RBCs (large arrow), spherocytosis (small arrow), and polychromtophilic RBCs (double arrow).

 

Figure 2
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Figure 2. The RBC nuclear abnormalities associated with the marrow response to severity of the immune hemolysis can be seen in this view in addition to the marked RBC findings noted on the previous image.

 

Figure 3
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Figure 3. Marked spherocytosis (arrow) is evident, and nucleated RBCs can be seen in the peripheral smear at various stages of maturation (double arrow).

 

Figure 4
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Figure 4. The marrow response to the hemolysis is shown in this view with nucleated RBCs (large arrow), spherocytes (small arrow), and poychromatophilic RBCs (double arrow).

 

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Related ASH Education Book Articles logo
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Related ASH-SAP Chapter:space logo
Chapter 16: Transfusion medicine

This Article
Right arrow Figures Only
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Google Scholar
Right arrow Articles by Lazarchick, J.
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PubMed
Right arrow Articles by Lazarchick, J.
Related Collections
Right arrow Hemolytic Disorders
Right arrow Special Pediatric
Right arrow Related ASH-SAP Chapter
Right arrowRelated Image Bank Image Sets
Right arrowRelated ASH Education Book Articles
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Copyright © 2009 by the American Society of Hematology.