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RBC morphology in thalassemia

View larger version (106K): [in this window] [in a new window]   Figure 1. Peripheral smear from a child with hemoglobin of 7.5 g/dl, RBC of 5.9 x 106/ul and an MCV of 47 fL consistent with a diagnosis of thalassemia. The marked RBC microcytosis and hypochromia are evident. The child had received an RBC transfusion prior to smear being performed accounting for the dual population of RBCs. A spherocyte (arrow) is present on the smear and is of donor origin.

View larger version (103K): [in this window] [in a new window]   Figure 2. A hypochromic polychromatophilic RBC (arrow) is shown in addition to the RBC abnormalities already mentioned.

View larger version (126K): [in this window] [in a new window]   Figure 3. A more typical polychromatophilic RBC is seen in the right upper portion of the image. Occasional target cells are also noted.

View larger version (116K): [in this window] [in a new window]   Figure 4. The dimorphic population of the RBCs following the transfusion in this patient.

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This Article Figures Only Services Similar articles in this journal Alert me to new content in the Image Bank Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Lazarchick, J. Search for Related Content PubMed Articles by Lazarchick, J. Related Collections Hemolytic Disorders Related ASH-SAP Chapter Related Image Bank Image Sets Related ASH Education Book Articles Social Bookmarking                   What's this?