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ASH Image Bank (2009); doi:10.1182/ashimagebank-2009-9-00044
Copyright © 2009 by the American Society of Hematology.
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Atlas Image Set

Sickle cell disease – RBC morphology

John Lazarchick, M.D.


Figure 1
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Figure 1. Peripheral smear from a patient with sickle cell disease illustrates the spectrum of RBC findings in this disorder including sickle cells, polychromatophilic RBCs, target cells, and Howell-Jolly bodies.

 

Figure 2
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Figure 2. In addition to the RBC findings noted in Fig. 1, this image shows a nucleated RBC (arrow).

 

Figure 3
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Figure 3. Polychromatophilic RBCs (reticulocytes) are present (small single arrow). Target cell (large single arrow) and sickle cell (double arrow) can be seen in this view.

 

Figure 4
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Figure 4. Crescent-shaped sickle cells are noted (double arrow). Several RBCs with Howell-Jolly bodies are also present. One has two such inclusions (single arrow).

 

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Related ASH-SAP Chapter:space logo
Chapter 6: Hemolytic anemias

This Article
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PubMed
Right arrow Articles by Lazarchick, J.
Related Collections
Right arrow Hemolytic Disorders
Right arrow Related ASH-SAP Chapter
Right arrowRelated Image Bank Image Sets
Right arrowRelated ASH Education Book Articles
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Copyright © 2009 by the American Society of Hematology.